Tpn Nutrition Case Study - 1274 Words

t has been pointed out that there is a possibility of deficiencies in trace elements during TPN nutrition control procedures without the addition of trace elements, and, in fact, in several foreign countries have developed TPN solutions containing plural trace elements for the purposes of therapy. (9) In this studied we applied a TPN solution to a group of rats with a trace element deficient diet and compared it with a group of rats with a TPN diet supplemented with iron, zinc, copper, manganese, and iodine were compared while the rats were alive. First, with respect to blood properties (RBC, Hb, Hct, MCV, and MCH), the levels of group A, B, and C significantly decreased compared to those of group D. Groups A, B, and C showed signs of†¦show more content†¦However, iron concentrations in the brain, heart, liver, testis, and tibia in group B tended to shower higher values than those of group A, even though they didn’t reach the same levels as group D. It was suggested t hat if the nutrition management was continued for a longer period of time and the trace element solution was used, that there is a possibility that the blood fluid properties and iron deficiency state of the subjects could have been improved. The occurrence of deficiencies during the time of TPN treatments which have been cured by zinc has been reported numerous times, (2, 3) and it is widely accepted that adding zinc to TPN solutions is necessary. When comparing groups A and C, the zinc concentration in group A in plasma and the tibia’s of subjects showed a significantly lower value, and it is possible that the TPN treatment made zinc deficiency worse. The level of zinc in group B (the trace element mixed solution group) was almost the same as group D. These doses seemed to be proper for alleviating zinc deficiency. ALP uses zinc as a coenzyme, and it has been reported that when zinc is intraperitoneally administered to zinc deficient rats, ALP levels increase markedly. (11) In this experiment ALP levels were elevated by administration of the trace element mixed solution. This change in ALP levels was consistent with the change in plasma zinc concentration levels. Declines is zinc concentration in blood plasma or ALP would reflect zincShow MoreRelatedMalnutrition Increases Morbidity and Mortality Essay1183 Words   |  5 Pagesthat can worsen the case in elderly population. Malnutrition increases morbidity, mortality, complication rates, and the length of stay in hospitals.2 The prevalence rate of hospital malnutrition ranges between 20% to 60% and among outpatient is 7% to 16%. Disease-related malnutrition has become an economical issue. In Europe, it costs up to $125 billion every year. 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